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Regional heterogeneity of Bnc2 mRNA abundance in the mouse brain Quantitative analysis of Bnc2 expression levels (normalized transcripts per million, nTPM) across distinct brain regions, sourced from The protein atlas <t>bulk</t> <t>RNA-seq</t> dataset. Anatomical structures are color-coded and grouped into major divisions: cerebral cortex, olfactory bulb, hippocampal formation, amygdala, basal ganglia, thalamus, hypothalamus, midbrain, pons and medulla, cerebellum, and corpus callosum (white matter). Bars represent the mean nTPM value, and dots indicate individual sample replicates, demonstrating expression variability within each region. Data are presented as mean ± SD.
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Regional heterogeneity of Bnc2 mRNA abundance in the mouse brain Quantitative analysis of Bnc2 expression levels (normalized transcripts per million, nTPM) across distinct brain regions, sourced from The protein atlas <t>bulk</t> <t>RNA-seq</t> dataset. Anatomical structures are color-coded and grouped into major divisions: cerebral cortex, olfactory bulb, hippocampal formation, amygdala, basal ganglia, thalamus, hypothalamus, midbrain, pons and medulla, cerebellum, and corpus callosum (white matter). Bars represent the mean nTPM value, and dots indicate individual sample replicates, demonstrating expression variability within each region. Data are presented as mean ± SD.
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Regional heterogeneity of Bnc2 mRNA abundance in the mouse brain Quantitative analysis of Bnc2 expression levels (normalized transcripts per million, nTPM) across distinct brain regions, sourced from The protein atlas bulk RNA-seq dataset. Anatomical structures are color-coded and grouped into major divisions: cerebral cortex, olfactory bulb, hippocampal formation, amygdala, basal ganglia, thalamus, hypothalamus, midbrain, pons and medulla, cerebellum, and corpus callosum (white matter). Bars represent the mean nTPM value, and dots indicate individual sample replicates, demonstrating expression variability within each region. Data are presented as mean ± SD.

Journal: iScience

Article Title: BNC2 as a putative transcriptional coordinator linking energy state to neural circuits

doi: 10.1016/j.isci.2026.115733

Figure Lengend Snippet: Regional heterogeneity of Bnc2 mRNA abundance in the mouse brain Quantitative analysis of Bnc2 expression levels (normalized transcripts per million, nTPM) across distinct brain regions, sourced from The protein atlas bulk RNA-seq dataset. Anatomical structures are color-coded and grouped into major divisions: cerebral cortex, olfactory bulb, hippocampal formation, amygdala, basal ganglia, thalamus, hypothalamus, midbrain, pons and medulla, cerebellum, and corpus callosum (white matter). Bars represent the mean nTPM value, and dots indicate individual sample replicates, demonstrating expression variability within each region. Data are presented as mean ± SD.

Article Snippet: We thank the Allen Institute for Brain Science for providing open access to the Mouse Whole-Brain Transcriptomic Cell Type Atlas (MERFISH, Allen Brain Cell Atlas; knowledge.brain-map.org ), and the Human Protein Atlas consortium for publicly available bulk RNA-seq data ( www.proteinatlas.org ).

Techniques: Expressing, RNA Sequencing, Olfactory